In the cerebrospinal fluid, the liquid around the brain and the spinal cord, more unbound magnesium is present than in blood plasma. That distance holds even while the figure in blood drifts about inside its customary range. Cobaltitello gathers what has been written on the matter and sets beside it the one wording cleared in the European Union for magnesium and the nervous system.
Continue to the long versionHanging in the cavities of the brain is a tissue with a heavy blood flow, the choroid plexus. Its uppermost cell layer is cemented shut along its edges, so that nothing passes between the cells into the fluid. Whatever arrives there has taken the route through the inside of those cells beforehand.
Lay the unbound share in the cerebrospinal fluid beside the one in blood plasma, and according to the published series the first sits about one and a half times higher. When the blood figure drifts inside its ordinary range, the fluid figure follows that movement only faintly. The literature therefore speaks of a compartment kept on its own terms.
Of all this, nothing turns up in European law. What stands there is one sentence, assessed and taken into a list, and that sentence applies exactly as it is filed there:
“Magnesium contributes to normal functioning of the nervous system”
EU-authorized wording · Regulation (EU) No 432/2012, entry 242 of the Union list.
Fluid that washes around the brain and the spinal cord does not arise from blood simply seeping through. It is made, and made at a place that carries a name of its own in anatomy. That making is the reason the contents of the two compartments differ — not only for magnesium, but for this ion especially plainly.
The covering layer of the choroid plexus forms tight seals where its cells meet. That does away with the comfortable route dissolved particles take in many other tissues: the gap between two neighboring cells. What remains is the way straight through the cell interior, and that way calls for membrane proteins of its own on each side of the cell. Because the cell builds this equipment itself, it has a say in how much arrives on the far side.
The number in blood cannot be worked back from the number in the cerebrospinal fluid, and just as little the other way round. That is precisely the observation the literature sets down: two compartments parted by one cell layer carry different figures, and the one follows the other only in muted form. For everyday purposes this counsels above all a certain reserve toward any single laboratory number, from whichever of the two compartments it comes.
Everything named so far — choroid plexus, covering layer, membrane proteins, ratio of figures — comes from physiological review articles. Not one of these terms occurs in the authorized wording, and not one of them may be read as a claim of its own about a food. The cleared text reads, unaltered:
“Magnesium contributes to normal functioning of the nervous system”
EU-authorized wording · Regulation (EU) No 432/2012.
The word normal draws a ceiling over the statement. What is meant is the course of things as physiology describes it in adults with no particular history. Nothing above and beyond that is being said, and the sentence names no condition that would first have to be brought about.
What stands on this page is the shortened account. The reading folder runs the same sections at full length, lays the measurement series beside them as tables, and reproduces the register entry with its identifier and its source reference.
$49.00
One-time access · Digital information product
We undo a purchase within fourteen days of the day it was made, as an undertaking the publisher makes unprompted. A plain email is enough. The amount then travels back by the same route it came in on. The Refund Policy holds the written particulars.
What stands here is no substitute for an examination. A text knows no readings, no prior history and no list of medicines, and placing a personal situation calls for exactly that. Where the body changes, where medication is ongoing, and in pregnancy and while breastfeeding, a medical practice or a pharmacy is the address such questions belong to.
A food supplement stands beside a varied kitchen rather than replacing it. What the pack states for one day marks the upper limit, and products of that kind belong where children cannot reach them. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The marks Google and YouTube are the property of Alphabet Inc. They turn up here because part of the visits come from ads that the publisher of this page booked and paid for there. A booking of that sort is the purchase of advertising space, nothing further.
Neither of the two companies read these texts before publication, nor does anything behind this page amount to an endorsement, a collaboration or an editorial clearance from that quarter.
A passage in the text read ambiguously, the order raises a question, or you would like to know which of your details sit with us. Put it in your own words. The form hands the fields on to your email program; sending happens only there, by you.
The form is no obligation — a plain email to [email protected] does the job as well.